Alter genomic DNA with efficient editing

Alt-R™ CRISPR-Cas9 System—powered by the new Alt-R S.p. Cas9 Nuclease 3NLS!

The Alt-R CRISPR-Cas9 System includes all of the reagents you need for successful genome editing. Based on the endogenous S. pyogenes CRISPR-Cas9 pathway, the Alt-R CRISPR-Cas9 System offers numerous advantages over alternative methods:

  • • Save time and money with an efficient workflow and ready-to-use reagents.
  • • Increase potency and reduce off-target editing using CRISPR-Cas9 ribonucleoprotein.
  • • Adapt to your experimental needs with compatibility for lipofection or electroporation.

Improve genome editing performance

Alt-R™ CRISPR-Cas9 System

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Webinar

Alt-R™ CRISPR-Cas9 System ribonucleoprotein delivery

Struggling with low editing efficiency or delivery problems? IDT has developed a simple and affordable CRISPR-Cas9 solution that outperforms other methods. In this recorded presentation, we discuss use of a Cas9:tracrRNA:crRNA ribonucleoprotein (RNP) complex in genome editing experiments, and explain why it is the most efficient driver for genome editing compared to alternative methods. We also review RNP delivery using cationic lipids and electroporation, and provide tips for optimized transfection in your system.

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What our customers say

“After trying a variety of solutions, the IDT Alt-R CRISPR-Cas9 System was the most user friendly, and it generated superior results in our assays.”

—Large pharmaceutical customer

“The IDT modified crRNAs (Alt-R CRISPR-Cas9 System) work well in our assay and can generate fully penetrant phenotypes in transfected mammalian cells. They have allowed us to rapidly validate hits from pooled sgRNA screens without the need to construct expression plasmids or to generate lentivirus.”

—Large pharmaceutical customer