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The CRISPR Basics Handbook

Everything you need to know about CRISPR genome editing, from applications to how‑to guides


CRISPR genome editing continues to revolutionize biological sciences, from approved therapies to agriculture and industry, making it possible to edit the genome of almost any living organism. Because this technology can be overwhelming to those new to the field, we’ve assembled this handy guide to cut through the clutter and deliver useful information fast.

This comprehensive guide includes:

  • A brief history of CRISPR
  • An overview of common applications
  • How to get started with your CRISPR experiments
  • gRNA design guidelines
  • Cas enzyme considerations
  • Guidance on analyzing CRISPR genome editing results at on- and off-target sites
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