Enhance your CRISPR editing

Avoid the problems associated with plasmid delivery

Did you know that you can maximize genome editing efficiency by delivering CRISPR reagents as ribonucleoprotein (RNP) complexes? Get our cheat sheet to see all the advantages offered by RNPs.

“Overexpression of the guide RNA and Cas9 components in transfected vectors creates a standard problem for most biomedical systems—an unhealthy and often deleterious environment inside the targeted cells. Fortunately, we were introduced to the Alt-R CRISPR-Cas9 System and RNP delivery method developed by IDT. Now, not only has the frequency of single-nucleotide repair improved significantly, but the cells maintain a high degree of viability and the capability to carry out metabolic processes, including cell division, in a normal fashion.”

– Eric Kmiec, PhD,
Director, Gene Editing Institute, Helen F. Graham Cancer Center, Wilmington, DE, USA

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